Is VNS Therapy Right for Me?
Adding VNS Therapy to your treatment plan has been shown to work when other antidepressant treatments have not.1 Sometimes medications alone do not adequately relieve depression, or they relieve depression for a period of time, but then stop working.2 If multiple medications and other antidepressant treatments have not adequately or continuously relieved your depression, it may be time to discuss VNS Therapy with your psychiatrist as a long-term treatment option.

About Treatment Resistant Depression >>>
Not all depression is the same. Psychiatrists have found that antidepressant medications are effective in 60% to 75% of people overall. 2 When depression has not responded to 4 or more adequate antidepressant treatments, this is a common condition called treatment resistant depression, or TRD. Since TRD may have multiple causes, some people may require a different type of ongoing treatment for their depression.

Talking to Your Psychiatrist >>>
If you would like to know if you could benefit from adjunctive VNS Therapy for treatment resistant depression, talk to your psychiatrist. Click here to assess your depression and find out if VNS Therapy is right for you  Share the outcomes from the self-assessment with your psychiatrist during your next office visit.

Bipolar Depression >>>
Learn more about the use of VNS Therapy for bipolar treatment-resistant depression.

VNS Therapy & ECT >>>
VNS Therapy has been shown to succeed in people who have had ECT. A person who has VNS Therapy for treatment-resistant depression can have ECT later, if necessary. Learn more about the use of VNS Therapy and Electroconvulsive Therapy.

Frequently Asked Questions >>>

1. Rush AJ, Sackeim HA, Marangell LB, et al. Effects of 12 months of vagus nerve stimulation in treatment-resistant depression: a naturalistic study. Biol Psychiatry. 2005;58:355-363. 2. Fava M, Rush AJ, Trivedi MH, et al. Background and rationale for the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study. Psychiatr Clin North Am. 2003;26:457-494.

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The VNS Therapy System is indicated for use as an adjunctive therapy in reducing the frequency of seizures in adults and adolescents over 12 years of age with partial onset seizures, which are refractory to antiepileptic medications.

VNS Therapy (or the VNS Therapy System) is indicated for the adjunctive long-term treatment of chronic or recurrent depression for patients over the age of 18 who are experiencing a major depressive episode and have not had an adequate response to four or more adequate antidepressant treatments.