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This is a newsletter for people interested in learning more about VNS Therapy for chronic or recurrent treatment-resistant depression.

February 2008: Volume 4, Issue 1 - The February issue brings you an update on the Mental Health parity legislation, as well as information on a VNS Therapy clinical study that is currently underway to study various dosing levels. Also in this issue you will meet Susan and learn about her experience with VNS Therapy. A summary from a recently-published case study on long-term response with VNS Therapy is included, as well as information from Dr. Pamela Sullivan about the pulse generator battery life. The timely tip for February provides a reminder of the importance of exercise during the winter months. .
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September 2007: Volume 3, Issue 3 - The September issue brings you some of the most Frequently Asked Questions regarding VNS Therapy in treatment-resistant depression (TRD) that occur during the patient educational teleconferences that take place each month. Also in this issue you will meet John and learn about his experience with VNS Therapy. Highlights from the annual meetings of several national mental health consumer groups are included, and Dr. Steven Buser provides his perspective on important issues related to dosing with VNS Therapy. The timely tip for September provides an update on the National Depression Screening Day coming up in October.
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June 2007: Volume 3, Issue 2 - The June issue brings you VNS Therapy highlights from last month’s annual meeting of the American Psychiatric Association, plus information on the largest study ever to assess treatments for depression. Then, you’ll meet Lisa and read about her experience with VNS Therapy. Noted psychiatrist Dr. Karen Jacobs discusses the use of VNS Therapy in people with long-lasting depression. Plus you’ll learn how people like you decided to make VNS Therapy their next treatment step. A new feature, “Access Tips,” outlines how to persuade an employer to provide coverage for VNS Therapy. The timely tips for June provides suggestions for restless sleepers.
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March 2007: Volume 3, Issue 1 - The lead story describes Lauri's achievements during her first year of VNS Therapy. Noted psychiatrist John P. O’Reardon discusses the use of VNS Therapy in people with bipolar depression and explains how your doctor can help you get insurance coverage. Patients tell how they kept hope alive while waiting for their insurance companies to provide coverage for VNS Therapy-and how they helped the process along. And don’t miss the timely tip for March and other sources of information.
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December 2006: Volume 2, Number 7 -The December issue provides information on the Depression and Bipolar Support Alliance, the nation’s leading patient-directed organization focusing on depression and bipolar disorder. Inside, you’ll meet Paulette and hear about her experience with VNS Therapy. Noted psychiatrist Dr. Howard Houghton discusses the efficacy of VNS Therapy for people with recurrent depression. Patients answer questions about how they and their families heard about VNS Therapy. And don’t miss the tips for the dark days of December and other sources of information.
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October 2006: Volume 2, Number 6 -The October issue opens by highlighting exciting news about why VNS Therapy works when other treatments have failed. Inside, you’ll meet Janet and hear about her experience with VNS Therapy. Noted psychiatrist Dr. Darin Dougherty answers questions about dosing adjustment for VNS Therapy. Patients answer questions about how they obtained insurance coverage. Plus a helpful tip for fall and other sources of information.
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August 2006: Volume 2, Number 5 -The August issue opens by highlighting exciting news about VNS Therapy from recent scientific meetings. Inside, you’ll meet Jerry and hear about his experience with VNS Therapy. Noted psychiatrist Dr. David L. Dunner answers questions about the uses of electroconvulsive therapy (ECT) and VNS Therapy. Plus a helpful hot-weather tip and other sources of information.
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May 2006: Volume 2, Number 4 - The May issue opens with one psychiatrist’s insight on deciding when to recommend VNS Therapy. Inside, you’ll meet Laura and hear about her experience with VNS Therapy. Noted psychiatrist Dr. Scott Aaronson answers the question, “How can I tell if VNS Therapy is working?” Plus a helpful tip of the month and other sources of information.
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March 2006 : Volume 2, Number 3 - The March issue opens with a report on recent research seeking to identify the best treatment approaches for depression. Inside, you’ll meet Carol and hear about her experience with VNS Therapy. Noted psychiatrist Dr. Lauren Marangell answers questions about VNS Therapy in bipolar disorder and about battery life for the VNS Therapy pulse generator. Plus a helpful tip of the month and other sources of information.
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February 2006 : Volume 2, Number 2 - The February issue opens with some important research from 2005. Inside, you’ll meet Ann and hear about her experience with VNS Therapy. Noted psychiatrist Dr. David L. Dunner answers questions from patients. Plus an intriguing historical note about President Abraham Lincoln and depression.
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January 2006 : Volume 2, Number 1 - The New Year opens with an update on VNS Therapy for treatment-resistant depression (TRD). Inside, you’ll meet Cathy, a VNS Therapy patient. Dr. Charles Conway, psychiatrist, answers questions from patients on page 3. Plus tips and other sources of useful information.
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December 2005: Volume 1, Number 3 - Provides a report on important recent research on VNS Therapy. You’ll meet Marna and learn about her experience with VNS Therapy. Also includes "ask the patient" questions and answers along with an "ask the doctor" section where psychiatrist Mustafa Husain, MD, answers questions from patients on page 3.
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November 2005: Volume 1, Number 2 - Features events associated with National Depression Awareness Month, October 2005. You’ll meet Charles, and learn about his experience with VNS Therapy. Also, a noted psychiatrist answers frequently asked questions from patients. Plus tips and other sources of useful information.
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October 2005: Volume 1, Number 1 - Covers the July 2005 approval of VNS Therapy for use in people with chronic or recurrent depression. It features an interview with a VNS Therapy patient. A noted psychiatrist answers questions from patients. Plus tips and other sources of useful information.
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  UNITED STATES INDICATION FOR USE:
The VNS Therapy System is indicated for use as an adjunctive therapy in reducing the frequency of seizures in adults and adolescents over 12 years of age with partial onset seizures, which are refractory to antiepileptic medications.

VNS Therapy (or the VNS Therapy System) is indicated for the adjunctive long-term treatment of chronic or recurrent depression for patients over the age of 18 who are experiencing a major depressive episode and have not had an adequate response to four or more adequate antidepressant treatments.